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Matters needing attention in the use of lithium carbonate
Time：
2020/7/7
Lithium carbonate, an inorganic compound with the chemical formula Li2CO3, is a colorless monoclinic crystal or white powder. The density was 2.11g/cm3. Melting point 618 ℃. Soluble in dilute acid. It is slightly soluble in water and more soluble in cold water than in hot water. Insoluble in alcohol and acetone. It can be used to make ceramics, medicine, catalyst, etc. Commonly used materials for lithium ion batteries.
Effect and use
Lithium carbonate can significantly inhibit mania, improve the emotional disturbance of schizophrenia, and has no effect on the energy activities of normal people. The effect mechanism may be related to inhibiting the release of norepinephrine in the brain synapse and promoting reuptake, and has effect on increasing peripheral area cells. The small dose of lithium carbonate has certain therapeutic effect on uterine fibroids with menorrhagia, Low dose can also be used for acute bacillary dysentery. Lithium salt has no sedative effect. Generally, it is combined with chlorpromazine for severe acute manic patients, and then lithium carbonate is used only after acute symptoms are controlled.
usage
The general dosage of mania is 0.125-0.5g each time, three times a day. A small dose can be used at the beginning, and then it can be gradually increased to 1.5-2g, or even 3G. The persistent dose is 0.75-1.5g per day.
Oral administration of granulocytopenia and aplastic anemia, 300mg each time, three times a day. Menorrhagia: 0.6g on the first day of menstruation, 0.3g a day, divided into 3 times, a total of 3 days, acute bacillary dysentery 0.1g each time, three times a day, the first dose doubled
Side effects
There are dizziness, nausea, vomiting, abdominal pain, diarrhea and other side effects
matters needing attention
In case of accumulated poisoning, encephalopathy syndrome (vagueness, tremor, epilepsy) and coma, shock and kidney damage may occur. If the above situation occurs, the drug should be stopped immediately and aminophylline should be injected intravenously to promote the secretion of lithium.
During the period of lithium salt intake, lithium salt can not be used to promote the excretion of sodium salt in the elderly, otherwise, it is easy to cause kidney inflammation. Patients with cardiorenal disease and electrolyte disorder should not be used.
Instructions for use
Materials for the preparation of various high-purity lithium salts; raw materials for lithium-containing single crystals; materials for optical special glass, enamel industry, medicine, catalysts, color phosphors; materials for lithium-ion batteries.
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